F3 CLIA Kit for Human(Homo sapiens) | EIAab.comF3 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > F3(Gene name) > Human

F3 (Gene name),

Tissue factor (Protein name ), TF_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

F3;

Protein name:

Tissue factor(TF);

Alternative:

Thromboplastin;Coagulation factor III;

CD:

CD142;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

Function:

Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.

Subcellular Location:

Isoform 2 Secreted

Protein Attributes:

Sequence length:

295

Sequence:

50:

100:

150:

200:

250:

295:

EIFYIIGAVV | FVVIILVIIL | AISLHKCRKA | GVGQSWKENS | PLNVS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.62192

SMR:

P13726

String:

P13726

KEGG:

hsa:2152

STRING:

9606.ENSP00000334145

Pfam:

PF09294

MIM:

134390

Uniprot:

P13726

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ELISA Kit for Human TF

Cat.:

E0524r

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Packing:

96T

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ELISA Kit for Human TF

MSDS:

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ELISA Kit for Human TF

Cat.:

E0524h

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96T

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ELISA Kit for Human TF

Cat.:

E0524m

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Looking for manual.

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Packing:

96T

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ELISA Kit for Human TF

Cat.:

E0524b

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Packing:

96T

CLIA Kit for Human TF

MSDS:

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CLIA Kit for Human TF

Cat.:

U0524b

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MSDS:

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Packing:

96T

CLIA Kit for Human TF

Cat.:

U0524h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human TF

Cat.:

U0524m

Price:

Please sign in first.

MSDS:

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Packing:

96T

CLIA Kit for Human TF

Cat.:

U0524r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human TF

Cat.:

P0524Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TF

Cat.:

P0524Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human TF

Cat.:

P0524Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human TF

Protein for Human TF

Cat.:

R0524h

Price:

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Packing:

1mg

Purity:

>90%

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human tissue factor: cDNA sequence and chromosome localization of the gene."
Scarpati E.M. , Wen D. , Broze G.J. Jr. , Miletich J.P. , Flandermeyer R.R. , Siegel N.R. , Sadler J.E.
Biochemistry26:5234-5238(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade."
Morrissey J.H. , Fakhrai H. , Edgington T.S.
Cell50:129-135(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA."
Spicer E.K. , Horton R. , Bloem L. , Bach R. , Williams K.R. , Guha A. , Kraus J. , Lin T.C. , Nemerson Y. , Konigsberg W.H.
Proc. Natl. Acad. Sci. U.S.A.84:5148-5152(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Cloning and expression of human tissue factor cDNA."
Fisher K.L. , Gorman C.M. , Vehar G.A. , O'Brien D.P. , Lawn R.M.
Thromb. Res.48:89-99(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
5.

"Complete sequence of the human tissue factor gene, a highly regulated cellular receptor that initiates the coagulation protease cascade."
Mackman N. , Morrissey J.H. , Fowler B. , Edgington T.S.
Biochemistry28:1755-1762(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein."
Bogdanov V.Y. , Balasubramanian V. , Hathcock J. , Vele O. , Lieb M. , Nemerson Y.
Nat. Med.9:458-462(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
7.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
8.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
9.

SeattleSNPs variation discovery resource
Submitted (2002-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ALA-36 AND VAL-145
10.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
12.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Prostate.
13.

"Human tissue factor contains thioester-linked palmitate and stearate on the cytoplasmic half-cystine."
Bach R. , Konigsberg W.H. , Nemerson Y.
Biochemistry27:4227-4231(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BONDS;PALMITOYLATION AT CYS-277
14.

"Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells."
Eisenreich A. , Bogdanov V.Y. , Zakrzewicz A. , Pries A. , Antoniak S. , Poller W. , Schultheiss H.P. , Rauch U.
Circ. Res.104:589-599(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;INDUCTION
15.

"Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII."
Nadir Y. , Brenner B. , Fux L. , Shafat I. , Attias J. , Vlodavsky I.
Haematologica95:1927-1934(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HPSE
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
17.

"Structure of the extracellular domain of human tissue factor: location of the factor VIIa binding site."
Muller Y.A. , Ultsch M.H. , Kelley R.F. , de Vos A.M.
Biochemistry33:10864-10870(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 33-243
18.

"The crystal structure of the extracellular domain of human tissue factor refined to 1.7-A resolution."
Muller Y.A. , Ultsch M.H. , de Vos A.M.
J. Mol. Biol.256:144-159(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 33-243
19.

"The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor."
Banner D.W. , D'Arcy A. , Chene C. , Winkler F.K. , Guha A. , Konigsberg W.H. , Nemreson Y. , Kirchhofer D.
Nature380:41-46(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 33-251 IN COMPLEX WITH FVIIA
20.

"Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant."
Zhang E. , St Charles R. , Tulinsky A.
J. Mol. Biol.285:2089-2104(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 37-242 IN COMPLEX WITH FVIIA

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